In 2009 at the time of its establishment, Academic City College was a standalone facility in Ring Road, Accra that was popularly known for its affiliated programme with Sikkim Manipal University (SMU). Over the course of 9 years, Academic City College graduated over 3,000 students from over 23 countries in Africa. The college's alumni established themselves as distinguished professionals working at reputed organizations such as international banks, manufacturing firms, corporate offices, government departments and financial institutions in Ghana and West Africa.
In 2017, Academic City recognized the need to redefine premium tertiary education by integrating entrepreneurial thinking, innovative problem-solving, application-based learning, and a strong emphasis on ethical practices within the African context. With this renewed purpose, the institution repositioned itself and established a state-of-the-art campus to deliver transformative, modern-day education.